Description

Leucinostatin A CAS NO 82111-44-2 is a potent, non-ribosomal peptide antibiotic belonging to the peptaibol family, characterized by a high proportion of the amino acid leucine. This compound is of significant interest for its strong antifungal and cytotoxic properties, making it a valuable tool in biochemical and pharmacological research. It is primarily utilized by researchers in the life sciences, pharmaceutical development, and agricultural chemistry sectors for studying membrane interactions, developing novel therapeutics, and exploring biocontrol agents.

Application

• Biochemical Research: Used as a model ionophore to study pore formation and ion transport across lipid membranes.
• Antifungal Agent Development: Serves as a lead compound in the research and development of new antifungal pharmaceuticals and agrochemicals.
• Cell Biology Studies: Employed to investigate apoptosis and cytotoxicity mechanisms in various cell lines.
• Antimicrobial Screening: Acts as a reference standard in assays for discovering new antimicrobial agents.
• Pharmaceutical R&D: Utilized in preclinical studies to evaluate efficacy against drug-resistant fungal pathogens.
• Academic Research: A key reagent for universities and institutes studying non-ribosomal peptide synthesis and peptaibol bioactivity.

Basic Information

Product Name	Leucinostatin A
CAS No.	82111-44-2
Molecular Formula	C56H100N14O13
Molecular Weight	1153.5 g/mol
Synonyms	Leucinostatin A; Antibiotic A-21978C1; Peptaibol A-21978C1; Leucinostatin; NSC 326017; UNII-3J8L7T4Y5R
EINECS	Contact for details

Quality Control

Our Leucinostatin A is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and potency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. Due to its hygroscopic (moisture-sensitive) nature, the product should be kept under desiccant and allowed to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Biological Activity	Assayed; data on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.