Description

Benzeneacetic Acid, 3-Fluoro-α-Methyl-4-Nitro- is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by research and development chemists and process engineers working on novel active ingredients, where its unique substitution pattern enables precise structural modifications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, including potential anti-inflammatory and central nervous system (CNS) agents.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic cores in electronic and optoelectronic materials.
• Advanced Organic Synthesis: Employed in cross-coupling reactions, nucleophilic substitutions, and other transformations to introduce complex, multi-functionalized aromatic systems.
• Chemical Reference Standard: Used as a high-purity standard in analytical laboratories for method development and quality control of related compounds.

Basic Information

Product Name	Benzeneacetic Acid, 3-Fluoro-α-Methyl-4-Nitro-
CAS No.	81937-32-8
Molecular Formula	C9H8FNO4
Molecular Weight	213.16 g/mol
Synonyms	3-Fluoro-α-methyl-4-nitrophenylacetic acid; 2-(3-Fluoro-4-nitrophenyl)propanoic acid; 3-Fluoro-4-nitrophenylhydracrylic acid; 3-Fluoro-4-nitrohydratropic acid; (3-Fluoro-4-nitrophenyl)propanoic acid; α-Methyl-3-fluoro-4-nitrophenylacetic acid; 81937-32-8
EINECS	Contact for details

Quality Control

Our Benzeneacetic Acid, 3-Fluoro-α-Methyl-4-Nitro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), related substances, and residual solvents are provided and traceable to each lot. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); therefore, containers should be kept sealed under an inert gas blanket after opening and moisture ingress should be prevented.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.