Description

3,3-Didemethylpiperacillin is a key pharmaceutical intermediate and a structural analog of the broad-spectrum antibiotic piperacillin. This compound is of significant value in the research, development, and synthesis of advanced β-lactam antibiotics and related active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in the production of novel antibacterial agents and the exploration of new therapeutic pathways.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of piperacillin and its derivatives.
• Antibiotic Research & Development: Used in the discovery and structural modification of new β-lactam antibiotics to combat resistant bacterial strains.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in the manufacturing process of finished antibiotic drugs.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR) of penicillin and cephalosporin-class antibiotics.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.
• Fine Chemical Production: Supplied to specialty chemical companies for further functionalization and custom synthesis projects.

Basic Information

Product Name	3,3-Didemethylpiperacillin
CAS No.	81482-39-5
Molecular Formula	C23H27N5O7S
Molecular Weight	517.56 g/mol
Synonyms	(2S,5R,6R)-6-[[(2R)-2-[[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; Piperacillin Impurity; 3,3-Dimethyl-7-oxo-6-(2-phenyl-2-[(4-ethyl-2,3-dioxo-1-piperazinyl)formamido]acetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid; De-methyl Piperacillin Intermediate; Antibiotic Intermediate 81482-39-5
EINECS	Contact for details

Quality Control

Our 3,3-Didemethylpiperacillin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical intermediates. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.