Description

n-(7-Nitro-2,1,3-Benzoxadiazol-4-Yl)-L-Proline is a specialized heterocyclic amino acid derivative, serving as a key building block and fluorescent labeling reagent. Its core value lies in its unique structure, which combines the fluorescent properties of the nitrobenzoxadiazole (NBD) moiety with the chiral backbone of L-proline, enabling sensitive detection and analysis. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for developing novel probes, studying biochemical interactions, and synthesizing advanced intermediates.

Application

• Fluorescent Labeling Reagent: Used for tagging peptides, proteins, and other biomolecules to enable detection and imaging in biochemical assays.
• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of potential drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation Chemistry: Employed in the development of diagnostic probes and targeted therapeutic conjugates due to its reactive functional groups.
• Analytical Chemistry Standard: Acts as a reference standard or derivatization agent in chromatographic (HPLC, LC-MS) methods for amino acid analysis.
• Biochemical Research: Utilized in enzyme studies, receptor binding assays, and cellular imaging to investigate biological pathways and mechanisms.
• Material Science: Potential application in the development of advanced fluorescent polymers or sensors.

Basic Information

Product Name	n-(7-Nitro-2,1,3-Benzoxadiazol-4-Yl)-L-Proline
CAS No.	81432-12-4
Molecular Formula	C₁₄H₁₄N₄O₅
Molecular Weight	318.28 g/mol
Synonyms	NBD-Proline; L-Proline, N-(7-nitro-4-benzofurazanyl)-; 4-(N-(7-Nitro-2,1,3-benzoxadiazol-4-yl))-L-proline; N-(7-Nitro-2,1,3-benzoxadiazol-4-yl)-L-proline; NBD-L-Proline; 4-(N-(NBD))-L-proline; 7-Nitro-4-(L-prolyl)-2,1,3-benzoxadiazole; Fluorescent L-Proline derivative
EINECS	Contact for details

Quality Control

Our n-(7-Nitro-2,1,3-Benzoxadiazol-4-Yl)-L-Proline is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure compliance with exacting research and development standards. Certificates of Analysis (COA) detailing identity, purity, and specific impurities are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.