Description

2,2,2-Trifluoromethazolamide CAS NO 81428-88-8 is a high-purity fluorinated heterocyclic compound, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique reactivity imparted by the trifluoromethyl group, enabling the synthesis of complex molecules with enhanced metabolic stability and bioavailability. This compound is essential for research and development laboratories and production facilities in the pharmaceutical and agrochemical sectors, where it is used to build novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas like enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in developing next-generation herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Material Science: Serves as a precursor for specialty polymers and advanced materials requiring fluorine incorporation for specific properties like chemical resistance or low surface energy.
• Organic Synthesis: A versatile reagent for introducing the trifluoromethyl group into complex molecular architectures in academic and industrial R&D.
• Fluorine Chemistry Studies: Used as a reference standard or starting material in methodological development within synthetic fluorine chemistry.

Basic Information

Product Name	2,2,2-Trifluoromethazolamide
CAS No.	81428-88-8
Molecular Formula	C5H4F3N3O2S
Molecular Weight	227.16 g/mol
Synonyms	2,2,2-Trifluoro-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide; 5-(2,2,2-Trifluoroacetamido)-1,3,4-thiadiazole-2-sulfonamide; Trifluoromethazolamide; 2,2,2-Trifluoroacetamido-1,3,4-thiadiazole-5-sulfonamide; 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide, 2,2,2-trifluoro-; TFMZ; 81428-88-8; 2-Trifluoroacetamido-5-sulfamoyl-1,3,4-thiadiazole
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoromethazolamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for research and synthesis. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, supporting compliance with cGMP and other relevant regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.