Description

Alfuzosin Hydrochloride CAS NO 81403-68-1 is a selective α-1 adrenergic receptor antagonist of high pharmaceutical importance. This compound is the active pharmaceutical ingredient (API) in medications primarily used to treat the symptoms of benign prostatic hyperplasia (BPH). It is essential for pharmaceutical manufacturers and research institutions developing urological therapeutics. Consistent quality and reliable supply are critical for ensuring the efficacy and safety of the final drug product.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for the treatment of benign prostatic hyperplasia (BPH).
• Generic Drug Formulation: Serves as a key component in the production of generic versions of branded alfuzosin medications.
• Clinical Research: Utilized in preclinical and clinical studies for investigating new therapeutic applications or formulations.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Drug Discovery: Used as a pharmacological tool in research exploring α-1 adrenergic receptor pathways and related disorders.

Basic Information

Product Name	Alfuzosin Hydrochloride
CAS No.	81403-68-1
Molecular Formula	C19H27N5O4 • HCl
Molecular Weight	425.91 g/mol
Synonyms	Alfuzosin HCl; N-[3-[(4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furancarboxamide hydrochloride; Xatral (trade name); Uroxatral (trade name); SL 77.0499-10; Alfuzosine Hydrochloride; Alfuzosin Hydrochloride USP
EINECS	Contact for details

Quality Control

Our Alfuzosin Hydrochloride is manufactured under strict quality management systems. The product undergoes comprehensive analytical testing to ensure it meets high-purity pharmaceutical-grade standards, including potential compliance with USP/EP monographs. Each batch is supported by a detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles, available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.