Description

7-Chloro-4-Sulfobenzoxadiazole is a high-purity, specialized heterocyclic sulfonic acid derivative, identified by CAS NO 81377-20-0. This compound serves as a critical intermediate and derivatization reagent, valued for its reactive sulfonyl chloride group and fluorescent properties. It is essential for researchers and manufacturers in the pharmaceutical, analytical chemistry, and advanced material sectors who require precise molecular building blocks for synthesis and labeling applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and diagnostic agents.
• Analytical Derivatization Reagent: Used in HPLC and LC-MS for labeling and detecting amines, amino acids, and other biomolecules to enhance sensitivity and selectivity.
• Fluorescent Probe Synthesis: Serves as a core structure for developing fluorescent dyes and sensors used in bioimaging and cellular assays.
• Bioconjugation Chemistry: Employed to modify proteins, peptides, and oligonucleotides for research, diagnostics, and therapeutic applications.
• Material Science Research: Used in the development of advanced polymers and functional materials with specific sulfonic acid group properties.
• Chemical Synthesis: Acts as a versatile building block for creating sulfonamides and other complex organic molecules in research and development.

Basic Information

Product Name	7-Chloro-4-Sulfobenzoxadiazole
CAS No.	81377-20-0
Molecular Formula	C6H3ClN2O3S
Molecular Weight	218.62 g/mol
Synonyms	7-Chloro-2,1,3-benzoxadiazole-4-sulfonic acid; 4-Chloro-7-sulfobenzofurazan; SBD-Cl; 7-Chloro-4-sulfobenzofurazan; 4-Sulfo-7-chloro-2,1,3-benzoxadiazole; 7-Chloro-4-sulfobenzo-2,1,3-oxadiazole; DBDF-SO3H; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 7-Chloro-4-Sulfobenzoxadiazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.