Description

4-Chloro-7-Sulfobenzofurazan Ammonium Salt is a specialized heterocyclic organic compound that serves as a critical derivatization reagent and fluorescent labeling agent. Its core value lies in its ability to selectively react with primary amines and thiols, forming highly fluorescent adducts for sensitive detection and quantification. This makes it an essential tool for researchers and quality control professionals in pharmaceutical analysis, biochemical research, and environmental testing who require precise and reliable analytical methods.

Application

• HPLC and LC-MS Derivatization: Used as a pre-column or post-column derivatizing agent for the sensitive detection of amino acids, biogenic amines, peptides, and pharmaceuticals.
• Fluorescent Labeling in Biochemistry: Employed for tagging proteins, antibodies, and other biomolecules to enable fluorescence-based assays, imaging, and detection.
• Clinical Diagnostics: Applied in the development of diagnostic kits and assays for detecting biomarkers in biological samples.
• Environmental Analysis: Utilized for tracing and quantifying amine-containing pollutants or degradation products in water and soil samples.
• Food Safety Testing: Helps in the analysis of amino acids, biogenic amines (e.g., histamine), and other nitrogenous compounds in food products.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of genotoxic impurities or related substances in active pharmaceutical ingredients (APIs).
• Research & Development: Serves as a versatile building block and probe in organic synthesis and chemical biology research.

Basic Information

Product Name	4-Chloro-7-Sulfobenzofurazan Ammonium Salt
CAS No.	81377-14-2
Molecular Formula	C₆H₄ClN₃O₄S • xNH₃
Molecular Weight	Contact for details
Synonyms	4-Chloro-7-sulfobenz-2-oxa-1,3-diazole ammonium salt; SBD-F Ammonium Salt; 4-Chloro-7-sulfobenzofurazan, ammonium salt; Ammonium 4-chloro-7-sulfobenz-2-oxa-1,3-diazole; 4-Chloro-7-sulfobenz-2,1,3-oxadiazole ammonium salt; Benzofurazan, 4-chloro-7-sulfo-, ammonium salt; ABD-F (related compound); DBDF (related compound)
EINECS	Contact for details

Quality Control

Our 4-Chloro-7-Sulfobenzofurazan Ammonium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the high standards required for sensitive analytical applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.