Description

Imiloxan Hydrochloride is a selective α-2 adrenergic receptor antagonist of significant interest in pharmaceutical research and development. This compound is a crucial intermediate and reference standard for the synthesis and study of novel therapeutic agents targeting the central nervous system. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in neuropharmacology and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced drug candidates targeting adrenergic pathways.
• Reference Standard: Used for analytical method development, validation, and quality control (QC) in API manufacturing.
• Biochemical Research: Tool compound for in vitro and ex vivo studies investigating α-2 adrenoceptor function and signal transduction.
• Preclinical Development: Employed in pharmacological profiling and safety assessment studies during early drug discovery phases.
• Academic Research: Serves as a precise chemical reagent for university and institutional research into cardiovascular and neurological disorders.

Basic Information

Product Name	Imiloxan Hydrochloride
CAS No.	81167-16-0
Molecular Formula	C14H18N2O2 • HCl
Molecular Weight	282.77 g/mol
Synonyms	Imiloxan HCl; 2-(1,4-Benzodioxan-2-yl)-2-imidazoline hydrochloride; RS-21361; (2S)-2-[(1,4-Benzodioxan-2-yl)methyl]-4,5-dihydro-1H-imidazole hydrochloride; 2-(1,4-Benzodioxan-2-ylmethyl)-4,5-dihydro-1H-imidazole hydrochloride; 2-(2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)-2-imidazoline hydrochloride
EINECS	Contact for details

Quality Control

Our Imiloxan Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and NMR, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) are provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.