Description

Lenampicillin Hydrochloride is a semi-synthetic, broad-spectrum aminopenicillin antibiotic in its hydrochloride salt form, offering enhanced stability and solubility. Its primary value lies in its potent bactericidal activity against a wide range of Gram-positive and some Gram-negative pathogens, making it a critical intermediate and active pharmaceutical ingredient (API). This compound is essential for manufacturers in the pharmaceutical industry involved in the research, development, and production of advanced antibiotic formulations.

Application

• Active Pharmaceutical Ingredient (API): Primary use in the formulation of oral antibiotic medications.
• Pharmaceutical Intermediates: Serves as a key precursor in the synthesis of more complex antibiotic derivatives.
• Research & Development: Utilized in microbiological and pharmacological studies for evaluating new antibacterial therapies.
• Reference Standard: Employed as a high-purity standard in quality control laboratories for analytical method development and validation.
• Veterinary Medicine: Used in the development of antibacterial treatments for animal health.

Basic Information

Product Name	Lenampicillin Hydrochloride
CAS No.	80734-02-7
Molecular Formula	C21H27N3O7S • HCl
Molecular Weight	502.0 g/mol (as hydrochloride)
Synonyms	Lenampicillin HCl; (2S,5R,6R)-6-[[(2R)-2-Amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ester with 1-(cyclohexyloxycarbonyloxy)ethyl (2R)-2-amino-3-methylbutanoate hydrochloride; Varacillin; KBT-1585; Bacampicillin related compound B (Hydrochloride); Bacampicillin impurity B HCl
EINECS	Contact for details

Quality Control

Our Lenampicillin Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided, confirming identity, purity, and impurity profiles as per in-house specifications aligned with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can compromise stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.