Description

4-(1,1,2,3,3,3-Hexafluoropropoxy)Benzoic Acid is a specialized fluorinated aromatic carboxylic acid derivative, serving as a critical building block in advanced chemical synthesis. Its unique structure, featuring a hexafluoropropoxy side chain, provides exceptional chemical stability and specific reactivity sought after in high-performance applications. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reliable intermediates for complex syntheses.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the fluorinated group can improve efficacy and environmental persistence.
• Liquid Crystal Materials: Serves as a core component or side-chain modifier in the production of fluorinated liquid crystals for advanced display technologies.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart unique properties such as chemical resistance, low surface energy, and thermal stability.
• Organic Synthesis Building Block: A versatile reagent for introducing the 4-(hexafluoropropoxy)benzoic acid moiety into more complex molecular architectures in medicinal and materials chemistry.
• Surface Treatment & Coatings: Used in formulations for creating hydrophobic, oleophobic, and chemically resistant surface coatings.

Basic Information

Product Name	4-(1,1,2,3,3,3-Hexafluoropropoxy)Benzoic Acid
CAS No.	80397-17-7
Molecular Formula	C10H6F6O3
Molecular Weight	288.14 g/mol
Synonyms	4-(Hexafluoropropoxy)benzoic acid; Benzoic acid, 4-(1,1,2,3,3,3-hexafluoropropoxy)-; 4-(Perfluoropropoxy)benzoic acid; 4-(1H,1H,2H,3H,3H-Perfluoropropoxy)benzoic acid; p-(Hexafluoropropoxy)benzoic acid; 4-(HFP)benzoic acid; 80397-17-7; HFP-O-Ph-COOH
EINECS	Contact for details

Quality Control

Our production of 4-(1,1,2,3,3,3-Hexafluoropropoxy)Benzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and quantify purity. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.