Description

3-Fluoro-4-Iodobenzoic Acid is a high-purity halogenated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it an exceptionally versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its polarizable iodine atom.
• Cross-Coupling Reactions: The iodine moiety acts as an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create biaryl and other complex structures.
• Fluorination Chemistry Studies: Used as a model substrate in research to study the influence of ortho-iodo substituents on the reactivity and directing effects of fluorine in aromatic systems.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Fluoro-4-Iodobenzoic Acid
CAS No.	825-98-9
Molecular Formula	C7H4FIO2
Molecular Weight	266.01 g/mol
Synonyms	4-Iodo-3-fluorobenzoic Acid; Benzoic acid, 3-fluoro-4-iodo-; 3-Fluoro-4-iodobenzoic acid; 825-98-9; 3-Fluoro-4-iodobenzoicacid; 4-Iodo-3-fluorobenzoicacid; 3-Fluoro-4-jodbenzoesäure (German); Acide 3-fluoro-4-iodobenzoïque (French)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Iodobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	205 - 210 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.