Description

Ergoline-8-Carboxamide, 5,10-Didehydro-N,n-Diethyl-2,3-Dihydro-6-Methyl-, (8.Beta.)- is a high-purity ergoline derivative, a key structural motif in numerous pharmacologically active compounds. This compound is valued for its role as a critical advanced pharmaceutical intermediate in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development and production of specialized therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex ergot alkaloid-derived APIs and research compounds.
• Biochemical Research: Used as a reference standard or precursor in neurological and receptor-binding studies.
• Process Development: Serves as a critical material for scaling up synthetic routes in process chemistry and pilot plant production.
• Analytical Standard: Employed in method development and validation for quality control laboratories to ensure product purity and identity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Ergoline-8-Carboxamide, 5,10-Didehydro-N,n-Diethyl-2,3-Dihydro-6-Methyl-, (8.Beta.)-
CAS No.	800-25-9
Molecular Formula	C19H25N3O
Molecular Weight	311.42 g/mol
Synonyms	N,N-Diethyl-6-methyl-8β-ergolinecarboxamide; 8β-(N,N-Diethylcarbamoyl)-6-methylergoline; 5,10-Didehydro-N,N-diethyl-2,3-dihydro-6-methyl-8β-ergolinecarboxamide; Lysergamide, N,N-diethyl-6-methyl-; (8β)-5,10-Didehydro-N,N-diethyl-2,3-dihydro-6-methylergoline-8-carboxamide; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Ergoline-8-Carboxamide derivative is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling and spectroscopic identification. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to light and oxidation, prolonged exposure to air and light must be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.