Description

Penicillin V is a narrow-spectrum, acid-stable antibiotic belonging to the penicillin class, widely recognized for its efficacy against Gram-positive bacteria. Its primary commercial value lies in its role as a key active pharmaceutical ingredient (API) for the production of oral antibiotic formulations, ensuring reliable and consistent therapeutic outcomes. This product is essential for pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in the development and production of anti-infective medications.

Application

• Pharmaceutical API: Primary use as the active ingredient in oral antibiotic tablets, capsules, and liquid suspensions for treating streptococcal infections.
• Veterinary Medicine: Formulation of antibacterial treatments for livestock and companion animals.
• Research & Development: Used as a reference standard and biochemical tool in microbiological and pharmacological research.
• Fine Chemical Synthesis: Serves as a starting material or intermediate for the synthesis of more complex antibiotic derivatives.
• GMP Manufacturing: Supplied for use in Good Manufacturing Practice (GMP) certified facilities for regulated drug production.

Basic Information

Product Name	Penicillin V
CAS No.	87-08-1
Molecular Formula	C16H18N2O5S
Molecular Weight	350.39 g/mol
Synonyms	Phenoxymethylpenicillin; Penicillin V Potassium (salt form); Pen-Vee; V-Cillin; Phenoxymethylpenicillinic Acid; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Derivative; (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid
EINECS	201-722-6

Quality Control

Our Penicillin V is produced and tested to meet stringent pharmaceutical-grade standards. Quality assurance protocols are designed to ensure identity, purity, potency, and safety, with compliance to relevant pharmacopoeial monographs (such as USP, EP, BP) where applicable. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing results for assay, related substances, residual solvents, and microbiological attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
pH (suspension)	2.5 - 4.0
Specific Optical Rotation	+223° to +237°
Heavy Metals	≤ 20 ppm
Microbiological Enumeration	Complies with Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.