Description

2-Difluoromethylbenzoic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. Its unique difluoromethyl group adjacent to the carboxylic acid functionality makes it a critical intermediate for introducing fluorine atoms into target molecules, thereby modulating their physicochemical and biological properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting metabolic diseases and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoromethyl group can enhance bioavailability and environmental stability.
• Material Science Precursor: Serves as a monomer or modifier in the development of specialty polymers and liquid crystal materials with tailored performance characteristics.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a precursor for more complex fluorinated compounds in academic and industrial research laboratories.

Basic Information

Product Name	2-Difluoromethylbenzoic Acid
CAS No.	799814-32-7
Molecular Formula	C8H6F2O2
Molecular Weight	172.13 g/mol
Synonyms	2-(Difluoromethyl)benzoic Acid; Benzoic acid, 2-(difluoromethyl)-; o-Difluoromethylbenzoic Acid; 2-(Difluoromethyl)benzoic acid; 799814-32-7; Difluoromethylbenzoic acid (ortho-); 2-Carboxydifluoromethylbenzene
EINECS	Contact for details

Quality Control

Our 2-Difluoromethylbenzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.