Description

1-Palmitoyl-Sn-Glycero-2,3-Cyclic-Phosphate (Ammonium Salt) is a high-purity, synthetic phospholipid derivative, specifically a cyclic phosphatidic acid analogue. This compound is a critical biochemical tool and advanced intermediate for research and development in lipid signaling and membrane biology. It is primarily utilized by pharmaceutical researchers, academic institutions, and specialty chemical manufacturers focused on developing novel therapeutics and diagnostic agents.

Application

• Biochemical Research: As a potent and specific inhibitor of autotaxin (ATX) and a modulator of lysophosphatidic acid (LPA) receptor signaling pathways.
• Pharmaceutical Development: A key intermediate in the synthesis of novel drug candidates targeting cancer metastasis, fibrosis, and neuropathic pain.
• Lipidomics & Analytical Standards: Serves as a certified reference material (CRM) for mass spectrometry and chromatography in lipid analysis.
• Cell Biology Studies: Used to investigate cellular processes such as proliferation, migration, and survival in various cell lines.
• Formulation Science: A component in the development of advanced lipid-based drug delivery systems (e.g., liposomes, nanoparticles).
• Enzyme Inhibition Studies: A substrate or inhibitor in enzymatic assays to study phospholipase activity and related enzymes.

Basic Information

Product Name	1-Palmitoyl-Sn-Glycero-2,3-Cyclic-Phosphate (Ammonium Salt)
CAS No.	799268-71-6
Molecular Formula	C19H40NO6P
Molecular Weight	409.50 g/mol
Synonyms	1-Palmitoyl-2,3-cyclic phosphatidic acid ammonium salt; cPA (16:0) ammonium salt; Cyclic phosphatidic acid (16:0) ammonium salt; 1-Hexadecanoyl-sn-glycerol-2,3-cyclic phosphate ammonium salt; LPA analogue; Autotaxin inhibitor cPA; sn-Glycero-2,3-cyclic phosphate 1-palmitate ammonium salt; 2,3-Cyclic PA (16:0) NH4+ salt
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-Sn-Glycero-2,3-Cyclic-Phosphate (Ammonium Salt) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This material is hygroscopic (moisture-sensitive). For long-term storage, keep under an inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95% (Area %)
Water Content (KF)	≤2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.