Description

2-Fluoro-6-Iodo-3-Methylbenzoic Acid is a high-purity, multi-functional aromatic building block of significant interest in advanced organic synthesis. Its unique halogenated structure, featuring both fluorine and iodine substituents, makes it a valuable precursor for constructing complex molecules via cross-coupling reactions. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting new small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated benzoic acid scaffold.
• Material Science Precursor: Serves as a starting material for synthesizing specialized ligands, liquid crystals, and advanced organic polymers.
• Cross-Coupling Reactions: The iodine atom is an excellent handle for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira), while the fluorine can influence electronic properties and metabolic stability.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated intermediates.

Basic Information

Product Name	2-Fluoro-6-Iodo-3-Methylbenzoic Acid
CAS No.	796967-33-4
Molecular Formula	C8H6FIO2
Molecular Weight	280.04 g/mol
Synonyms	3-Methyl-2-fluoro-6-iodobenzoic Acid; 2-Fluoro-6-iodo-3-methylbenzoic Acid; Benzoic acid, 2-fluoro-6-iodo-3-methyl-; 796967-33-4; 2-Fluoro-6-iodo-m-toluic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-Iodo-3-Methylbenzoic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity (typically by HPLC), and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive and should be stored away from light to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.