Description

(3-Bromo-2-Fluoro-Phenyl)-Acetic Acid is a high-purity fluorinated and brominated aromatic building block essential for advanced organic synthesis. This compound matters as a versatile intermediate for introducing both halogen functionalities into complex molecular architectures, enabling precise structural modifications. It is critically needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, particularly in creating candidates for drug discovery and specialty crop protection agents.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the halogenated phenylacetic acid moiety contributes to biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for synthesizing fluorinated organic electronic materials and advanced display components.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings to create complex biaryl and conjugated systems.
• Chemical Research & Development: A valuable reagent in academic and industrial labs for exploring new synthetic methodologies and creating novel fluorinated compounds.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the scalable production of bespoke intermediates under cGMP or research-grade conditions.

Basic Information

Item	Detail
Product Name	(3-Bromo-2-Fluoro-Phenyl)-Acetic Acid
CAS No.	786652-63-9
Molecular Formula	C8H6BrFO2
Molecular Weight	233.04 g/mol
Synonyms	2-(3-Bromo-2-fluorophenyl)acetic acid; (3-Bromo-2-fluorophenyl)acetic acid; 3-Bromo-2-fluorobenzeneacetic acid; 2-Fluoro-3-bromophenylacetic acid; α-(3-Bromo-2-fluorophenyl)acetic acid; NSC 796079; BRN 7276978; F2198-0232
EINECS	Contact for details

Quality Control

Our (3-Bromo-2-Fluoro-Phenyl)-Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. For advanced applications, we can supply material that meets research-grade or custom purity specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 99.0% (High Purity Grade)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.