Description

Ethyl 5-Chloro-2-Fluorobenzoate is a high-purity fluorinated benzoate ester, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile chemical handle for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This intermediate is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty fine chemicals who require reliable, high-quality raw materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine and chlorine substituents enhance biological activity and stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Electronics: Acts as a starting material for synthesizing fluorinated organic semiconductors and charge-transport materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create biaryl structures.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new fluorination methodologies and heterocyclic chemistry.

Basic Information

Product Name	Ethyl 5-Chloro-2-Fluorobenzoate
CAS No.	773139-56-3
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	5-Chloro-2-fluorobenzoic Acid Ethyl Ester; Ethyl 5-Chloro-2-fluorobenzoate; Benzoic acid, 5-chloro-2-fluoro-, ethyl ester; 2-Fluoro-5-chlorobenzoic Acid Ethyl Ester; Ethyl 2-Fluoro-5-chlorobenzoate; 773139-56-3; 5-Chloro-2-fluorobenzoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Chloro-2-Fluorobenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.