Description

Ethyl 2,4-Dibromo-6-Fluorobenzoate is a high-purity fluorinated and brominated aromatic ester, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile, multi-functional building block that enables the efficient construction of complex molecules for demanding applications. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise halogenated intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those containing fluorinated and brominated aromatic cores, which are prevalent in drug discovery for their metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the introduction of halogen atoms can significantly enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated and brominated aromatic compounds used in electronic materials, such as liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) due to the presence of bromine atoms, allowing for selective functionalization.
• Organic Synthesis & Chemical Research: A versatile reagent for academic and industrial R&D labs exploring novel synthetic pathways, heterocyclic chemistry, and the development of new fluorinated compounds.
• Specialty Polymer Modifier: Can be incorporated as a monomer or modifier to impart specific properties like flame retardancy or altered refractive index in high-performance polymers.

Basic Information

Product Name	Ethyl 2,4-Dibromo-6-Fluorobenzoate
CAS No.	773139-30-3
Molecular Formula	C9H7Br2FO2
Molecular Weight	325.96 g/mol
Synonyms	Benzoic acid, 2,4-dibromo-6-fluoro-, ethyl ester; Ethyl 2,4-dibromo-6-fluorobenzoate; 2,4-Dibromo-6-fluorobenzoic acid ethyl ester; Ethyl 2,4-dibromo-6-fluorobenzoate; Ethyl α,2,4-tribromo-6-fluorobenzoate (incorrect but common misnomer); 6-Fluoro-2,4-dibromobenzoic acid ethyl ester; EDFB (abbreviation); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our Ethyl 2,4-Dibromo-6-Fluorobenzoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.