Description

Ethyl 4-Chloro-2-(Trifluoromethyl)Benzoate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. Its molecular structure, featuring both chloro and trifluoromethyl substituents, provides unique electronic and steric properties critical for developing novel active compounds. This intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for creating new molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides and fungicides, where the trifluoromethyl group enhances lipophilicity and biological efficacy.
• Liquid Crystal & OLED Material Research: Used in the synthesis of fluorinated aromatic cores for electronic materials, contributing to improved performance in display and lighting technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitution reactions to construct complex, value-added aromatic systems.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new reaction methodologies and creating compound libraries for screening.

Basic Information

Product Name	Ethyl 4-Chloro-2-(Trifluoromethyl)Benzoate
CAS No.	773139-28-9
Molecular Formula	C10H8ClF3O2
Molecular Weight	252.62 g/mol
Synonyms	Ethyl 4-Chloro-2-(trifluoromethyl)benzoate; Benzoic acid, 4-chloro-2-(trifluoromethyl)-, ethyl ester; 4-Chloro-2-(trifluoromethyl)benzoic Acid Ethyl Ester; 2-Trifluoromethyl-4-chlorobenzoic Acid Ethyl Ester; Ethyl 4-Chloro-α,α,α-trifluoro-o-toluate; ECTB; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-2-(Trifluoromethyl)Benzoate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets exacting R&D and production standards. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.