Description

Ethyl 3-Chloro-5-Fluorobenzoate is a high-purity fluorinated aromatic ester building block of significant importance in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials, where the introduction of halogenated aromatic motifs is required. We supply this critical intermediate to the global market with a focus on consistent quality and reliable supply chain support.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the chloro-fluoro substitution pattern enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes.
• Polymer Chemistry: Employed to introduce halogenated benzoate groups into polymer chains, modifying properties like thermal stability, solubility, and refractive index for specialty plastics and coatings.
• Chemical Research & Development: A valuable reagent for method development, cross-coupling reactions (e.g., Suzuki, Stille), and exploring new synthetic pathways in academic and industrial R&D labs.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex, halogenated dyes and pigments that require specific light-fastness and color properties.

Basic Information

Product Name	Ethyl 3-Chloro-5-Fluorobenzoate
CAS No.	773138-93-5
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	3-Chloro-5-fluorobenzoic Acid Ethyl Ester; Ethyl 3-Chloro-5-fluorobenzoate; Benzoic acid, 3-chloro-5-fluoro-, ethyl ester; 5-Fluoro-3-chlorobenzoic Acid Ethyl Ester; Ethyl 5-Fluoro-3-chlorobenzoate; 773138-93-5; Ethyl 3-Chloro-5-fluorobenzoate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Chloro-5-Fluorobenzoate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring the material meets the stringent requirements of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.