Description

Ethyl 2-(Trifluoromethyl)-4-Methoxybenzoate is a high-purity, synthetically valuable fluorinated aromatic ester. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for the development of novel active ingredients. It is primarily sought by R&D laboratories and fine chemical manufacturers in the pharmaceutical and agrochemical sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a fluorinated building block for developing novel organic electronic materials with specific dielectric and luminescent properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and ester hydrolysis/transformation to create complex, functionalized benzoic acid derivatives.
• Chemical Research & Development: Utilized in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for high-throughput screening.

Basic Information

Product Name	Ethyl 2-(Trifluoromethyl)-4-Methoxybenzoate
CAS No.	773138-36-6
Molecular Formula	C11H11F3O3
Molecular Weight	248.20 g/mol
Synonyms	Ethyl 2-(Trifluoromethyl)-4-methoxybenzoate; 4-Methoxy-2-(trifluoromethyl)benzoic Acid Ethyl Ester; Benzoic acid, 2-(trifluoromethyl)-4-methoxy-, ethyl ester; Ethyl 4-methoxy-α,α,α-trifluoro-o-toluate; 2-Trifluoromethyl-4-methoxybenzoic acid ethyl ester; ETMFB (abbreviation)
EINECS	Contact for details

Quality Control

Our Ethyl 2-(Trifluoromethyl)-4-Methoxybenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and GC-MS and NMR for identity confirmation, to ensure it meets exacting R&D and production standards. A detailed Certificate of Analysis (COA) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.