Description

Benzoic Acid, 5-(Chlorocarbonyl)-2-Fluoro- (9Ci) is a high-value fluorinated benzoic acid derivative, specifically functionalized with a reactive acid chloride group. This compound serves as a critical pharmaceutical intermediate and building block for synthesizing more complex molecules in advanced research and development. It is primarily utilized by pharmaceutical, agrochemical, and specialty chemical manufacturers for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorine atoms for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine moiety can improve efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Polymer Modification: The reactive acid chloride group allows for incorporation into polymer chains to create specialty polyesters, polyamides, or coatings with specific properties.
• Chemical Research & Development: A versatile reagent in medicinal chemistry and material science for constructing complex molecular architectures via amide or ester bond formation.
• Fluorinated Dye & Pigment Synthesis: Intermediate for producing dyes and pigments with improved lightfastness and chemical resistance.

Basic Information

Product Name	Benzoic Acid, 5-(Chlorocarbonyl)-2-Fluoro- (9Ci)
CAS No.	773100-75-7
Molecular Formula	C8H4ClFO3
Molecular Weight	202.57 g/mol
Synonyms	2-Fluoro-5-(chlorocarbonyl)benzoic acid; 5-(Chlorocarbonyl)-2-fluorobenzoic acid; 2-Fluoroterephthalic acid chloride; 2-Fluoro-5-carboxybenzoyl chloride; 4-Fluorophthalic acid 4-chloride; 2-Fluoroisophthaloyl chloride (isomer); Terephthaloyl chloride, 2-fluoro- (related); 5-Carboxy-2-fluorobenzoyl chloride
EINECS	Contact for details

Quality Control

Our production of Benzoic Acid, 5-(Chlorocarbonyl)-2-Fluoro- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise customer specifications. Certificates of Analysis (COA) documenting all critical parameters are provided and can be tailored to support regulatory filings in pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis of the acid chloride group. Keep away from moisture, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.