Description

1-(4-Fluoro-Phenyl)-Cyclopropanecarboxylic Acid is a high-purity fluorinated cyclopropane derivative, a crucial building block in modern synthetic chemistry. Its unique structure, combining a cyclopropane ring with a fluorinated aromatic system, makes it an essential intermediate for creating complex molecules with targeted biological activity. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom and rigid cyclopropane scaffold can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials that require fluorinated aromatic components for specific thermal or electronic properties.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags or molecular probes to study biological processes and protein interactions.

Basic Information

Product Name	1-(4-Fluoro-Phenyl)-Cyclopropanecarboxylic Acid
CAS No.	773100-29-1
Molecular Formula	C10H9FO2
Molecular Weight	180.18 g/mol
Synonyms	4-Fluorophenylcyclopropanecarboxylic Acid; (4-Fluorophenyl)cyclopropanecarboxylic Acid; 1-(4-Fluorophenyl)cyclopropanecarboxylic Acid; Cyclopropanecarboxylic acid, 1-(4-fluorophenyl)-; p-Fluorophenylcyclopropanecarboxylic Acid; 1-(p-Fluorophenyl)cyclopropanecarboxylic Acid; 4-Fluoro-alpha,α-cyclopropylbenzenecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 1-(4-Fluoro-Phenyl)-Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.