Description

3-Fluoro-2-(trifluoromethyl)benzonitrile is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both fluorine and a trifluoromethyl group on the benzonitrile core, makes it a critical intermediate for developing novel compounds with tailored properties. This compound is primarily utilized by pharmaceutical and agrochemical research organizations seeking to incorporate fluorinated motifs to modulate bioavailability, metabolic stability, and binding affinity in new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or precursor for synthesizing specialty polymers, liquid crystals, and organic electronic materials requiring specific dielectric and optical properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring novel fluorination chemistry and creating compound libraries for high-throughput screening.
• Ligand and Catalyst Design: Useful for constructing sophisticated ligands in coordination chemistry and catalysis, leveraging the electron-withdrawing nature of the substituents.

Basic Information

Product Name	3-Fluoro-2-(trifluoromethyl)benzonitrile
CAS No.	771581-62-5
Molecular Formula	C8H3F4N
Molecular Weight	189.11 g/mol
Synonyms	2-Cyano-6-fluorobenzotrifluoride; 3-Fluoro-2-(trifluoromethyl)phenyl cyanide; 2-(Trifluoromethyl)-3-fluorobenzonitrile; Benzonitrile, 3-fluoro-2-(trifluoromethyl)-; 3-Fluoro-α,α,α-trifluoro-o-tolunitrile
EINECS	Contact for details

Quality Control

Every batch of our 3-Fluoro-2-(trifluoromethyl)benzonitrile is produced and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency suitable for demanding research and scale-up processes. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.