Description

4-[3,5-Bis(Trifluoromethyl)Phenyoxy]Benzoic Acid is a high-value fluorinated aromatic compound, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring multiple trifluoromethyl groups, is engineered to impart enhanced metabolic stability, lipophilicity, and electronic properties to target molecules. This specialty intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl groups improve biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a core component in the production of fluorinated liquid crystals for high-performance displays (LCDs).
• Organic Electronics: Building block for electron-transport materials, semiconductors, and other components in OLEDs and organic photovoltaics.
• Advanced Material Research: Utilized in academic and industrial R&D for creating novel polymers, ligands for catalysis, and specialty coatings with unique surface properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring fluorinated aromatic scaffolds.

Basic Information

Product Name	4-[3,5-Bis(Trifluoromethyl)Phenyoxy]Benzoic Acid
CAS No.	762286-35-1
Molecular Formula	C16H8F6O3
Molecular Weight	362.22 g/mol
Synonyms	4-[3,5-Bis(trifluoromethyl)phenoxy]benzoic acid; Benzoic acid, 4-[3,5-bis(trifluoromethyl)phenoxy]-; 4-(3,5-Bis(trifluoromethyl)phenoxy)benzoic acid; 4-(3,5-Bis(trifluoromethyl)phenoxy)benzoic acid; 762286-35-1; 4-(3,5-Bis(trifluoromethyl)phenoxy)-benzoic acid; 4-(3,5-Bis(trifluoromethyl)phenoxy)benzoic acid
EINECS	Contact for details

Quality Control

Our 4-[3,5-Bis(Trifluoromethyl)Phenyoxy]Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.