Description

Methyl 2-(Benzyloxy)-4-Fluorobenzoate is a high-purity fluorinated aromatic ester building block of significant importance in advanced organic synthesis. Its core value lies in its versatile structure, which incorporates both a benzyl-protected phenolic group and a fluorine atom, making it a critical intermediate for constructing complex molecules. This compound is primarily needed by research and development chemists and process scale-up teams within the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic cores used in electronic display and lighting technologies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated benzoate derivatives.
• Academic & Institutional Research: Utilized in university and government labs for methodological studies in fluorination chemistry and cross-coupling reactions.
• Chemical Library Development: A valuable component for creating diverse screening libraries in early-stage drug discovery.

Basic Information

Product Name	Methyl 2-(Benzyloxy)-4-Fluorobenzoate
CAS No.	753922-57-5
Molecular Formula	C15H13FO3
Molecular Weight	260.26 g/mol
Synonyms	4-Fluoro-2-(benzyloxy)benzoic acid methyl ester; Methyl 4-fluoro-2-(phenylmethoxy)benzoate; Benzoic acid, 4-fluoro-2-(phenylmethoxy)-, methyl ester; 2-Benzyloxy-4-fluorobenzoic acid methyl ester; Methyl O-benzyl-4-fluorosalicylate
EINECS	Contact for details

Quality Control

Our Methyl 2-(Benzyloxy)-4-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Impurity	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.