Description

1-(3-(Trifluoromethyl)Benzyl)-1H-Pyrazole-4-Carboxylicacid is a high-value, multi-functional heterocyclic building block characterized by its pyrazole core and trifluoromethylbenzyl substituent. This compound is essential for research and development in advanced organic synthesis, particularly for introducing specific steric and electronic properties into target molecules. It is primarily utilized by pharmaceutical, agrochemical, and advanced materials chemists seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and anti-inflammatory drug discovery programs.
• Agrochemical Synthesis: Serves as a crucial building block for creating novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazole moiety.
• Ligand and Catalyst Development: Used in organometallic chemistry to synthesize specialized ligands for catalysis and material science applications.
• Functional Material Precursor: Employed in the research and production of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe: Utilized in academic and industrial R&D to create molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: A starting material for bespoke chemical synthesis services catering to specialized client requirements.

Basic Information

Product Name	1-(3-(Trifluoromethyl)Benzyl)-1H-Pyrazole-4-Carboxylicacid
CAS No.	752222-88-1
Molecular Formula	C12H9F3N2O2
Molecular Weight	270.21 g/mol
Synonyms	1-[(3-(Trifluoromethyl)phenyl)methyl]-1H-pyrazole-4-carboxylic acid; 1-(3-(Trifluoromethyl)benzyl)-1H-pyrazole-4-carboxylic acid; 1H-Pyrazole-4-carboxylic acid, 1-[(3-(trifluoromethyl)phenyl)methyl]-; 752222-88-1; 1-(3-Trifluoromethyl-benzyl)-1H-pyrazole-4-carboxylic acid; 1-(3-(Trifluoromethyl)benzyl)pyrazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(3-(Trifluoromethyl)Benzyl)-1H-Pyrazole-4-Carboxylicacid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.