Description

4-Chloro-2,3-Difluoro-5-Hydroxybenzoicacid is a high-purity, multi-functional aromatic carboxylic acid derivative, distinguished by its unique halogenated and hydroxylated structure. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for the synthesis of complex organic molecules. It is essential for research and development chemists and production facilities in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the difluoro and chloro substituents contribute to biological activity.
• Liquid Crystal & OLED Materials: Acts as a precursor for the synthesis of fluorinated aromatic cores used in electronic display technologies.
• Polymer Modification: Serves as a functional monomer or cross-linking agent to introduce specific properties into polymer chains.
• Organic Synthesis Building Block: Utilized in medicinal chemistry and material science research for constructing complex, multi-substituted benzene derivatives.
• Coordination Chemistry Ligand: The carboxylic acid and hydroxyl groups make it a potential ligand for metal complexes in catalytic applications.

Basic Information

Product Name	4-Chloro-2,3-Difluoro-5-Hydroxybenzoicacid
CAS No.	749230-50-0
Molecular Formula	C7H3ClF2O3
Molecular Weight	208.55 g/mol
Synonyms	5-Hydroxy-4-chloro-2,3-difluorobenzoic acid; 4-Chloro-2,3-difluoro-5-hydroxybenzoic acid; Benzoic acid, 4-chloro-2,3-difluoro-5-hydroxy-; 2,3-Difluoro-5-hydroxy-4-chlorobenzoic acid; 4-Chloro-2,3-difluoro-5-hydroxy-benzoic acid; 749230-50-0; 4-Chloro-2,3-difluoro-5-hydroxybenzoic acid (ACI)
EINECS	Contact for details

Quality Control

Our 4-Chloro-2,3-Difluoro-5-Hydroxybenzoicacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications requiring GMP-grade intermediates and research-standard chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to atmospheric moisture. Store away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.