Description

Benzoic Acid, 2,5-Difluoro-3-Hydroxy- is a fluorinated hydroxybenzoic acid derivative, a high-value synthetic intermediate prized for its unique substitution pattern. This compound matters for its role in introducing fluorine atoms and phenolic functionality into complex molecular architectures, enabling the fine-tuning of physical, chemical, and biological properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of advanced active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators where fluorine substitution enhances bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in advanced electronic displays and organic light-emitting diodes (OLEDs), improving performance and durability.
• Polymer Modification: Incorporated as a monomer or additive to create specialty polymers with enhanced thermal stability, chemical resistance, or specific surface properties.
• Complex Ligand Synthesis: Utilized in organometallic chemistry and catalysis to develop sophisticated chelating agents and catalysts.
• Academic & Contract Research: A valuable reagent for methodological studies and discovery chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Benzoic Acid, 2,5-Difluoro-3-Hydroxy-
CAS No.	749230-40-8
Molecular Formula	C7H4F2O3
Molecular Weight	174.10 g/mol
Synonyms	3-Hydroxy-2,5-difluorobenzoic acid; 2,5-Difluoro-3-hydroxybenzoic acid; 2,5-Difluoro-3-hydroxy-benzoic acid; 2,5-Difluoro-3-hydroxybenzoic acid (ACI); 2,5-Difluoro-3-hydroxybenzoic acid (9CI); Benzoic acid, 2,5-difluoro-3-hydroxy-; 749230-40-8 (CAS)
EINECS	Contact for details

Quality Control

Every batch of 2,5-Difluoro-3-hydroxybenzoic acid is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.