Description

3,5-Difluoropicolinic Acid is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring two fluorine atoms on the pyridine ring, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoropyridine moiety enhances biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the development of organic electronic materials, such as ligands for OLEDs or molecular semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorinated probes for studying biological mechanisms and diagnostics.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3,5-Difluoropicolinic Acid
CAS No.	745784-04-7
Molecular Formula	C6H3F2NO2
Molecular Weight	159.09 g/mol
Synonyms	3,5-Difluoropyridine-2-carboxylic Acid; 2-Pyridinecarboxylic acid, 3,5-difluoro-; 3,5-Difluoro-2-pyridinecarboxylic acid; Picolinic acid, 3,5-difluoro-; 745784-04-7; 3,5-Difluoropicolinate
EINECS	Contact for details

Quality Control

Our 3,5-Difluoropicolinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability, consistency, and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.