Description

trans-4-[2-(4-Fluorophenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and proprietary drug formulations.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthetic routes for the production of fluorinated steroid analogs and other complex bioactive molecules.
• Organic Chemistry Research: Used in academic and industrial R&D for method development, catalysis studies, and exploring structure-activity relationships (SAR).
• Process Chemistry & Scale-Up: Employed in pilot plant and commercial manufacturing processes where high regioselectivity and stereochemical purity are required.
• Reference Standard: Acts as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical analysis.

Basic Information

Product Name	trans-4-[2-(4-Fluorophenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid
CAS No.	736136-55-3
Molecular Formula	C15H17FO3
Molecular Weight	264.29 g/mol
Synonyms	trans-4-(2-(4-Fluorophenyl)-2-oxoethyl)cyclohexanecarboxylic acid; 4-[(4-Fluorobenzoyl)methyl]cyclohexanecarboxylic acid (trans); 2-(4-Fluorophenyl)-2-oxoethyl-4-cyclohexanecarboxylic acid; 736136-55-3; 4-(2-(4-Fluorophenyl)-2-oxoethyl)cyclohexanecarboxylic acid; (1r,4r)-4-[2-(4-fluorophenyl)-2-oxoethyl]cyclohexane-1-carboxylic acid; (trans)-4-[2-(4-Fluorophenyl)-2-oxoethyl]cyclohexanecarboxylic acid
EINECS	Contact for details

Quality Control

Our trans-4-[2-(4-Fluorophenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality standards are designed to meet the rigorous demands of pharmaceutical development and cGMP-compliant production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.