Description

cis-3-[2-Oxo-2-(3-Trifluoromethylphenyl)Ethyl]Cyclohexane-1-Carboxylic Acid CAS NO 735275-41-9 is a high-value, synthetically derived carboxylic acid featuring a trifluoromethylphenyl ketone moiety. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block for medicinal chemistry research. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Synthesis: Used in the development of enzyme inhibitors due to its carboxylic acid and ketone functional groups.
• Agrochemical Intermediate: Potential application in the synthesis of advanced herbicides and pesticides leveraging the trifluoromethyl group's stability and lipophilicity.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands or organocatalysts for asymmetric synthesis.
• Material Science Precursor: Can be utilized to synthesize monomers for specialty polymers with unique thermal and chemical resistance properties.

Basic Information

Product Name	cis-3-[2-Oxo-2-(3-Trifluoromethylphenyl)Ethyl]Cyclohexane-1-Carboxylic Acid
CAS No.	735275-41-9
Molecular Formula	C₁₆H₁₇F₃O₃
Molecular Weight	314.30 g/mol
Synonyms	3-[2-Oxo-2-[3-(trifluoromethyl)phenyl]ethyl]cyclohexanecarboxylic acid, cis-; Cyclohexanecarboxylic acid, 3-[2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl]-, cis-; 735275-41-9; 3-(2-Oxo-2-(3-(trifluoromethyl)phenyl)ethyl)cyclohexanecarboxylic acid; cis-3-(2-(3-(Trifluoromethyl)benzoyl)ethyl)cyclohexanecarboxylic acid; TFMP-Cyclohexane Carboxylic Acid Derivative; (1r,3s)-3-[2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl]cyclohexane-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our cis-3-[2-Oxo-2-(3-Trifluoromethylphenyl)Ethyl]Cyclohexane-1-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and cGMP-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.