Description

4'-Trifluoromethoxy-Biphenyl-3-Carboxylic Acid is a high-purity, functionalized biphenyl derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the biphenyl scaffold with a carboxylic acid group and a trifluoromethoxy substituent, enabling precise molecular design. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require sophisticated intermediates for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a core component or side-chain modifier in the production of advanced liquid crystal displays (LCDs) due to its rigid biphenyl structure.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors, OLEDs, and photovoltaic materials.
• Advanced Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with tailored thermal and chemical resistance properties.
• Chemical Research & Development: A versatile scaffold for constructing complex molecules in academic and industrial R&D settings for various high-value applications.

Basic Information

Product Name	4'-Trifluoromethoxy-Biphenyl-3-Carboxylic Acid
CAS No.	728919-12-8
Molecular Formula	C14H9F3O3
Molecular Weight	282.22 g/mol
Synonyms	[3-(4-Trifluoromethoxyphenyl)]benzoic Acid; 3'-Carboxy-4'-(trifluoromethoxy)biphenyl; 4'-(Trifluoromethoxy)biphenyl-3-carboxylic Acid; Biphenyl-3-carboxylic acid, 4'-(trifluoromethoxy)-; 3-Biphenylcarboxylic acid, 4'-trifluoromethoxy-; 728919-12-8; 4-Trifluoromethoxy-biphenyl-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4'-Trifluoromethoxy-Biphenyl-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.