Description

6-(2-Trifluoromethylphenyl)-Nicotinic Acid CAS NO 726136-58-9 is a high-value, fluorinated nicotinic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring a trifluoromethylphenyl moiety, is essential for modulating the physicochemical and biological properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its aromatic and fluorinated structure.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for bespoke synthesis projects requiring fluorinated aromatic compounds.

Basic Information

Product Name	6-(2-Trifluoromethylphenyl)-Nicotinic Acid
CAS No.	726136-58-9
Molecular Formula	C13H8F3NO2
Molecular Weight	267.20 g/mol
Synonyms	2-(Trifluoromethyl)phenyl)nicotinic acid; 6-[2-(Trifluoromethyl)phenyl]pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 6-[2-(trifluoromethyl)phenyl]-; Nicotinic acid, 6-(2-trifluoromethylphenyl)-; 6-(2-Trifluoromethylphenyl)-3-pyridinecarboxylic acid; 6-(α,α,α-Trifluoro-o-tolyl)nicotinic acid
EINECS	Contact for details

Quality Control

Every batch of 6-(2-Trifluoromethylphenyl)-Nicotinic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.