Description

3-Fluoro-5-Iodobenzoic Acid is a high-purity halogenated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging the bioactivity of halogenated aromatics.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its ability to modify molecular polarity and conformation.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D labs as a standard reagent for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Coordination Chemistry Ligand: The carboxylic acid group allows it to act as a ligand for metal complexes used in catalysis or material science.

Basic Information

Product Name	3-Fluoro-5-Iodobenzoic Acid
CAS No.	723294-74-4
Molecular Formula	C7H4FIO2
Molecular Weight	265.01 g/mol
Synonyms	5-Iodo-3-fluorobenzoic Acid; Benzoic acid, 3-fluoro-5-iodo-; 3-Fluoro-5-iodobenzoic acid; 3-F-5-I-BA; 3-Fluoro-5-iodo-benzoic acid; 723294-74-4; 5-Iodo-3-fluoro-benzoic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Iodobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.