Description

trans-2-(2,5-Difluorophenyl)Cyclopropane-1-Carboxylic Acid CAS NO 701914-06-9 is a high-purity, fluorinated cyclopropane carboxylic acid derivative. This compound serves as a critical chiral building block and advanced pharmaceutical intermediate in modern organic synthesis. It is primarily required by research and development laboratories and production facilities in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides that leverage the difluorophenyl moiety for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Intermediate for synthesizing specialty polymers and liquid crystals with unique optical and electronic properties.
• Chemical Biology Probes: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a probe molecule in biochemical assays.

Basic Information

Product Name	trans-2-(2,5-Difluorophenyl)Cyclopropane-1-Carboxylic Acid
CAS No.	701914-06-9
Molecular Formula	C10H8F2O2
Molecular Weight	198.17 g/mol
Synonyms	(1R,2S)-2-(2,5-Difluorophenyl)cyclopropanecarboxylic Acid; (1S,2R)-2-(2,5-Difluorophenyl)cyclopropanecarboxylic Acid; trans-2-(2,5-Difluorophenyl)cyclopropanecarboxylic Acid; 2-(2,5-Difluorophenyl)cyclopropanecarboxylic Acid; 701914-06-9; Difluorophenyl Cyclopropane Carboxylic Acid; DFPC Acid
EINECS	Contact for details

Quality Control

Our trans-2-(2,5-Difluorophenyl)Cyclopropane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and impurity profile analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.