Description

Idazoxan is a selective and potent α-2 adrenergic receptor antagonist. This compound is a critical research tool in neuroscience and pharmacology for studying receptor function and signal transduction pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and contract research organizations (CROs) for preclinical investigations into neurological and cardiovascular systems.

Application

• Pharmacological Research: A key reference standard and tool compound for studying α-2 adrenoceptor mechanisms in the central and peripheral nervous systems.
• Neuroscience Studies: Used in experimental models to investigate the role of α-2 receptors in mood regulation, cognition, and pain perception.
• Drug Discovery & Development: Serves as a lead compound or comparator in the development of novel therapeutics targeting adrenergic pathways.
• Biochemical Assays: Employed in in vitro receptor binding and functional assays to characterize new chemical entities.
• Academic & Clinical Research: Supports fundamental research into autonomic nervous system function and related disorders.
• Reference Standard: Used for analytical method development, validation, and quality control in laboratory settings.

Basic Information

Product Name	Idazoxan
CAS No.	79944-58-4
Molecular Formula	C11H13N3O2
Molecular Weight	219.24 g/mol
Synonyms	Idazoxan; RX 781094; 2-(1,4-Benzodioxan-2-yl)-2-imidazoline; 2-(1,4-Benzodioxan-2-yl)-4,5-dihydro-1H-imidazole; Idazoxan hydrochloride (salt form); Benzodioxanyl imidazoline; EINECS 279-358-0
EINECS	279-358-0

Quality Control

Our Idazoxan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.