Description

Idazoxan Hydrochloride is a selective α-2 adrenergic receptor antagonist of significant research and pharmaceutical interest. This compound is a critical tool for investigating adrenergic signaling pathways and their roles in various physiological and neurological processes. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and fine chemical manufacturers engaged in neuroscience and cardiovascular research.

Application

• Pharmaceutical Research & Development: A key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel therapeutics targeting the central nervous system.
• Neuroscience Studies: Used extensively in preclinical research to study the function of α-2 adrenoceptors in mood regulation, cognition, and neuroprotection.
• Cardiovascular Research: Employed to investigate the role of α-2 receptors in blood pressure regulation and vascular tone.
• Biochemical Assay Development: Serves as a precise ligand in receptor binding assays and high-throughput screening (HTS) platforms.
• Metabolic Studies: Utilized in research exploring the influence of adrenergic systems on insulin secretion and glucose metabolism.
• Reference Standard: Provides a high-purity compound for analytical method development, validation, and quality control in GMP/GLP environments.

Basic Information

Product Name	Idazoxan Hydrochloride
CAS No.	79944-56-2
Molecular Formula	C11H13ClN2O•HCl
Molecular Weight	273.15 g/mol
Synonyms	Idazoxan HCl; 2-(1,4-Benzodioxan-2-yl)-2-imidazoline hydrochloride; RX 781094; Idazoxan hydrochloride; 2-(1,4-Benzodioxan-2-yl)-4,5-dihydro-1H-imidazole hydrochloride; EINECS 279-358-3
EINECS	279-358-3

Quality Control

Our Idazoxan Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation (IR, NMR) to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.