Description

2-[(Trifluoromethyl)Sulfonyl]Benzoic Acid is a high-value, multifunctional fluorinated aromatic building block characterized by its benzoic acid core substituted with a powerful electron-withdrawing trifluoromethanesulfonyl group. This unique structure makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where enhanced stability, lipophilicity, and specific electronic properties are required. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas requiring fluorinated motifs for metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethylsulfonyl group contributes to biological activity and environmental persistence.
• Ligand and Catalyst Precursor: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and charge-transport layers, due to its strong electron-accepting nature.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for custom synthesis houses serving the life sciences and advanced materials sectors.

Basic Information

Product Name	2-[(Trifluoromethyl)Sulfonyl]Benzoic Acid
CAS No.	79676-59-8
Molecular Formula	C8H5F3O4S
Molecular Weight	254.18 g/mol
Synonyms	2-((Trifluoromethyl)sulfonyl)benzoic acid; Benzoic acid, 2-[(trifluoromethyl)sulfonyl]-; α-(Trifluoromethylsulfonyl)benzoic acid; 2-(Trifluoromethanesulfonyl)benzoic acid; o-(Trifluoromethylsulfonyl)benzoic acid; TFSBA; 2-TFMS-Benzoic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-[(Trifluoromethyl)Sulfonyl]Benzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by techniques such as HPLC, NMR, and IR spectroscopy is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.