Description

2-(4-Trifluoromethylphenyl)-2-Oxoacetic Acid is a specialized aromatic keto-acid derivative characterized by its trifluoromethylphenyl functional group. This compound serves as a high-value advanced pharmaceutical intermediate and a versatile building block for synthesizing complex organic molecules. It is primarily utilized in the research and development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials, where its unique structure imparts desirable properties to the final product.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers with specific electronic or optical properties.
• Chemical Research & Development: A versatile reagent for organic synthesis, including Friedel-Crafts acylation and other carbon-carbon bond-forming reactions in R&D laboratories.

Basic Information

Product Name	2-(4-Trifluoromethylphenyl)-2-Oxoacetic Acid
CAS No.	79478-02-7
Molecular Formula	C9H5F3O3
Molecular Weight	218.13 g/mol
Synonyms	α-Oxo-4-(trifluoromethyl)benzeneacetic Acid; 2-Oxo-2-[4-(trifluoromethyl)phenyl]acetic Acid; 4-(Trifluoromethyl)benzoylformic Acid; 4-(Trifluoromethyl)phenylglyoxylic Acid; (4-Trifluoromethylphenyl)oxoacetic Acid; p-Trifluoromethylphenylglyoxylic Acid; 79478-02-7 (CAS)
EINECS	Contact for details

Quality Control

Our 2-(4-Trifluoromethylphenyl)-2-Oxoacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for use as a pharmaceutical intermediate. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, ensure containers are properly sealed and handled with appropriate chemical safety precautions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.