Description

(3-Fluorophenyl)(Oxo)Acetic Acid is a versatile fluorinated aromatic keto acid building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a carboxylic acid and a ketone functional group on a fluorinated benzene ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Useful for synthesizing fluorinated probes and tags for imaging and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	(3-Fluorophenyl)(Oxo)Acetic Acid
CAS No.	79477-87-5
Molecular Formula	C8H5FO3
Molecular Weight	168.12 g/mol
Synonyms	2-Oxo-2-(3-fluorophenyl)acetic acid; 3-Fluorobenzoylformic acid; 3-Fluorophenylglyoxylic acid; (3-Fluorobenzoyl)formic acid; α-Oxo-3-fluorobenzeneacetic acid; 3-Fluorophenyl-oxo-acetic acid; 3-Fluorophenylglyoxalic acid; 3-Fluorobenzoic acid, α-oxo-
EINECS	Contact for details

Quality Control

Our (3-Fluorophenyl)(Oxo)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity (IR, NMR), and impurity profiles (HPLC) is provided with each shipment to guarantee supply reliability and technical compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.