Description

30-Hydroxyrifamycin W is a key semi-synthetic derivative and a crucial intermediate in the synthesis of advanced rifamycin antibiotics. This compound is valued for its role in developing potent antimicrobial agents with improved pharmacological profiles. It is primarily utilized by pharmaceutical R&D laboratories and manufacturers specializing in anti-tuberculosis and broad-spectrum antibacterial drugs.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of next-generation rifamycin-class antibiotics, such as rifampicin and rifabutin analogs.
• Antimicrobial Research: Used in biochemical and microbiological research to study structure-activity relationships (SAR) and develop new antibacterial therapies.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step manufacturing process of complex antibiotic APIs.
• Reference Standard: Employed as a high-purity analytical standard in quality control (QC) and regulatory testing for antibiotic production.

Basic Information

Product Name	30-Hydroxyrifamycin W
CAS No.	79473-23-7
Molecular Formula	C39H49NO13
Molecular Weight	739.80 g/mol
Synonyms	30-Hydroxy-rifamycin W; Rifamycin W, 30-hydroxy-; 30-Hydroxy-27-demethoxy-27-oxorifamycin; (12Z,14E,24E)-(2S,12S,13S,14R,15S,16S,17R,18R,19S,20S,21S,22R,23S,26R)-6,9,15,17,19,21,23-Heptahydroxy-13-methoxy-2,4,12,16,18,20,22,26-octamethyl-1-oxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-5-yl acetate; 30-Hydroxy Rifamycin W
EINECS	Contact for details

Quality Control

Our 30-Hydroxyrifamycin W is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	Yellow to orange-red powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.