Description

Hydroxy-[Hydroxy-[[(2R,3S,5R)-3-Hydroxy-5-[4-(Hydroxyamino)-2-Oxo-Pyr Imidin-1-Yl]Oxolan-2-Yl]Methoxy]Phosphoryl]Oxy-Phosphoryl]Oxyphosphoni C Acid is a high-purity, chemically defined nucleotide analog crucial for advanced biochemical research and pharmaceutical development. This compound serves as a key building block and research tool for studying enzyme mechanisms, nucleic acid metabolism, and for the synthesis of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in antiviral, anticancer, and molecular biology applications.

Application

• Pharmaceutical Intermediate: Critical starting material or intermediate in the synthesis of novel nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used as a substrate, inhibitor, or probe in enzymatic studies, particularly for research involving polymerases, kinases, and other nucleic acid-metabolizing enzymes.
• Proteomics & Molecular Biology: Employed in the study of DNA/RNA synthesis, repair mechanisms, and as a tool for labeling nucleotides in various assays.
• Antiviral Agent Development: Serves as a core structural motif for developing nucleotide analogs that target viral replication enzymes.
• Reference Standard: Used as a high-purity certified reference standard (CRS) for quality control and analytical method development in pharmaceutical manufacturing.
• Academic Research: Fundamental research tool in university laboratories for investigating cellular signaling pathways and nucleotide biochemistry.

Basic Information

Product Name	Hydroxy-[Hydroxy-[[(2R,3S,5R)-3-Hydroxy-5-[4-(Hydroxyamino)-2-Oxo-Pyr Imidin-1-Yl]Oxolan-2-Yl]Methoxy]Phosphoryl]Oxy-Phosphoryl]Oxyphosphoni C Acid
CAS No.	78232-33-4
Molecular Formula	C9H17N4O15P3
Molecular Weight	538.16 g/mol
Synonyms	P1,P3-Di(adenosine-5') triphosphate; Diadenosine triphosphate; Ap3A; Diadenosine 5',5'''-P1,P3-triphosphate; Adenosine(5')triphospho(5')adenosine; 5'-Adenylyl triphospho-5'-adenosine; 5',5'''-Diadenosine triphosphate; P(1),P(3)-Bis(5'-adenosyl) triphosphate
EINECS	Contact for details

Quality Control

Our Hydroxy-[Hydroxy-[[(2R,3S,5R)-3-Hydroxy-5-[4-(Hydroxyamino)-2-Oxo-Pyr Imidin-1-Yl]Oxolan-2-Yl]Methoxy]Phosphoryl]Oxy-Phosphoryl]Oxyphosphoni C Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and stringent tests for residual solvents and impurities to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep desiccated under an inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.