Description

4-[4-(Trifluoromethyl)Phenoxy]Benzoic Acid is a high-value fluorinated aromatic intermediate with a distinct molecular architecture combining benzoic acid and trifluoromethylphenoxy functionalities. This compound matters for its role as a versatile building block in advanced organic synthesis, enabling the introduction of both lipophilic and electron-withdrawing properties into target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated monomers and mesogens used in display technologies and organic light-emitting diodes.
• Polymer Modification: Incorporated as a functional monomer to impart specific thermal, chemical, or surface properties to specialty polymers and coatings.
• Chemical Research & Development: A valuable reagent in academic and industrial labs for exploring new reaction pathways and creating complex fluorinated aromatic systems.

Basic Information

Product Name	4-[4-(Trifluoromethyl)Phenoxy]Benzoic Acid
CAS No.	78161-82-7
Molecular Formula	C14H9F3O3
Molecular Weight	282.21 g/mol
Synonyms	4-(4-Trifluoromethylphenoxy)benzoic acid; Benzoic acid, 4-[4-(trifluoromethyl)phenoxy]-; p-(p-Trifluoromethylphenoxy)benzoic acid; 4-(α,α,α-Trifluoro-p-tolyloxy)benzoic acid; 4-[4-(Trifluoromethyl)phenoxy]benzoic acid; 4-(4-Trifluoromethoxyphenoxy)benzoic acid (common misnomer); TFMPBA (abbreviation); CAS 78161-82-7
EINECS	Contact for details

Quality Control

Our 4-[4-(Trifluoromethyl)Phenoxy]Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.