Description

8,15-Leukotriene B4 is a specialized leukotriene metabolite, a key bioactive lipid mediator derived from arachidonic acid. This compound is essential for researchers investigating the complex pathways of inflammation, immune response, and related cellular signaling mechanisms. It is primarily utilized in advanced biochemical research, pharmaceutical development, and as a critical reference standard in analytical laboratories.

Application

• Biochemical Research: A vital tool for studying leukotriene biosynthesis, metabolism, and their role in inflammatory and immune responses.
• Pharmaceutical R&D: Used as a reference compound and intermediate in the development of novel anti-inflammatory and immunomodulatory therapeutics.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for method development and validation in HPLC, LC-MS, and other analytical techniques.
• Cell Signaling Studies: Employed in in vitro and ex vivo models to elucidate receptor interactions and downstream signaling cascades.
• Academic Research: Fundamental for university and institutional research projects focused on eicosanoid biology and pathophysiology.

Basic Information

Product Name	8,15-Leukotriene B4
CAS No.	77667-08-4
Molecular Formula	C₂₀H₃₂O₄
Molecular Weight	336.47 g/mol
Synonyms	8,15-DiHETE; (5Z,8Z,10E,12E,14Z)-8,15-Dihydroxyicosa-5,8,10,12,14-pentaenoic acid; 8,15-Dihydroxyeicosatetraenoic acid; 8,15-DiHETrE; Leukotriene B4 metabolite; 8,15-LTB4; 8(S),15(S)-DiHETE
EINECS	Contact for details

Quality Control

Our 8,15-Leukotriene B4 is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing batch-specific results are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in ethanol, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.