Description

Pelargonoyl Cyclic Decapeptide Polymyxin M(1) is a synthetic lipopeptide derivative, structurally related to the polymyxin class of antibiotics. This compound is significant for its potential as a research-grade biochemical tool in the study of bacterial membrane interactions and antimicrobial mechanisms. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in developing novel anti-infective agents and studying peptide chemistry.

Application

• Antimicrobial Research: Serves as a key reference standard and active compound in studies targeting Gram-negative bacteria.
• Pharmaceutical Development: Used in preclinical research for the design and efficacy testing of new polymyxin-based or modified peptide antibiotics.
• Biochemical Mechanism Studies: Employed to investigate the interaction of cationic peptides with bacterial lipopolysaccharides (LPS) and cell membranes.
• Quality Control & Analytical Standards: Functions as a high-purity certified reference material (CRM) for HPLC, LC-MS, and other analytical methods in QC laboratories.
• Academic Research: Utilized in university labs for teaching and advanced research in medicinal chemistry, microbiology, and peptide synthesis.

Basic Information

Product Name	Pelargonoyl Cyclic Decapeptide Polymyxin M(1)
CAS No.	77554-83-7
Molecular Formula	C58H98N16O13
Molecular Weight	1211.5 g/mol (approx.)
Synonyms	Polymyxin M(1) Pelargonoyl Derivative; N-Pelargonoyl-polymyxin M1; Cyclic Decapeptide Polymyxin M1 Derivative; Pelargonoyl-Polymyxin M1; Antibiotic Peptide Derivative; PMX M(1) analog; Research-grade Polymyxin
EINECS	Contact for details

Quality Control

Our Pelargonoyl Cyclic Decapeptide Polymyxin M(1) is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity determination and MS for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.