Description

Triadenylyl-(2'-3')-Adenylyl-Cytidylic Acid is a defined trinucleotide sequence, specifically a 2'-3' linked adenyl-adenyl-cytidylic acid. This compound is a crucial biochemical reagent used as a substrate, standard, or intermediate in enzymatic and molecular biology research. It is primarily utilized by research institutions, diagnostic manufacturers, and pharmaceutical companies engaged in nucleic acid chemistry, enzyme kinetics studies, and oligonucleotide synthesis. The product is supplied as a high-purity material to ensure reliable and reproducible experimental results.

Application

• Enzymatic Research Substrate: Used as a specific substrate for studying the activity, kinetics, and inhibition of ribonucleases (RNases), polymerases, and other nucleic acid-modifying enzymes.
• Molecular Biology Standards: Serves as a well-defined reference standard in chromatography (HPLC, LC-MS) and capillary electrophoresis for method development and quality control of oligonucleotides.
• Biochemical Synthesis Intermediate: Acts as a building block or intermediate in the chemical and enzymatic synthesis of longer oligonucleotides and RNA analogs.
• Diagnostic Development: Employed in the research and development of diagnostic assays and kits that involve nucleic acid detection or amplification processes.
• Structural Studies: Used in biophysical and structural biology research to investigate RNA folding, stability, and protein-RNA interactions.

Basic Information

Product Name	Triadenylyl-(2'-3')-Adenylyl-Cytidylic Acid
CAS No.	77354-26-8
Molecular Formula	C30H36N15O19P3
Molecular Weight	995.60 g/mol
Synonyms	Adenylyl-(2'→3')-adenylyl-(2'→3')-cytidine 5'-monophosphate; pA(2'-5')pA(2'-5')pC; 2'-3' Linked ApApC; AAA-Cytidylic Acid (2'-3' linked); Trinucleotide ApApC; Oligoadenylate Cytidylate; Research Grade ApApC; 2',3'-Oligoadenylate
EINECS	Contact for details

Quality Control

Our Triadenylyl-(2'-3')-Adenylyl-Cytidylic Acid is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and mass spectrometry for identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and related substance profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry atmosphere before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.