Description

Acamprosate Calcium is the calcium salt of N-acetyl homotaurine, a synthetic compound with a chemical structure analogous to the endogenous neurotransmitter γ-aminobutyric acid (GABA). This product is a critical active pharmaceutical ingredient (API) valued for its role in supporting abstinence maintenance in alcohol dependence. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of neurological and addiction treatment medications. Our supply ensures high purity and batch-to-batch consistency for reliable formulation.

Application

• Pharmaceutical Active Ingredient: Primary use in the manufacture of prescription medications for alcohol dependence therapy.
• Neurological Research: Used as a reference standard and investigational compound in studies related to GABAergic systems and addiction pathways.
• Formulation Development: Serves as the key component in the R&D of solid oral dosage forms, such as enteric-coated tablets.
• Generic Drug Production: Essential for companies producing bioequivalent versions of branded acamprosate calcium drugs.
• Clinical Trial Material: Supplied as GMP-grade material for use in Phase I-III clinical studies.
• Analytical Testing: Employed as a high-purity standard in quality control laboratories for HPLC, LC-MS, and other analytical methods.

Basic Information

Product Name	Acamprosate Calcium
CAS No.	77337-73-6
Molecular Formula	C10H20CaN2O8S2 • xH2O
Molecular Weight	Anhydrous: 400.48 g/mol
Synonyms	Calcium Acetylhomotaurinate; N-Acetylhomotaurine Calcium Salt; Acamprosate Calcium Salt; Campral (Brand Name); AOTA Calcium; 3-Acetamidopropane-1-sulfonic Acid Calcium Salt; Calcium 3-Acetamidopropanesulfonate; Acamprosatum Calcique
EINECS	Contact for details

Quality Control

Our Acamprosate Calcium is manufactured under strict quality management systems. It is typically supplied to meet pharmaceutical-grade specifications, with testing aligned to major pharmacopoeial standards such as USP and EP. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms to standard
Identification (Calcium)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Microbial Enumeration	Complies with EP/USP
pH (5% solution)	5.0 - 7.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.